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Blood Components

Page history last edited by PBworks 12 years, 11 months ago
                                              Blood Product Comparison

Whole blood
  • Rarely used unless more than 25% of total blood volume is lost
  • Available in 500 mL bags
  • Avoid if fluid overload is a concern
  • Hemorrhage
  • Trauma
  • Major burns
Packed Red Blood Cells
  • Prepared by removing 90% of plasma around cells and adding anticoagulant
  • Available in 250 mL bags
  • Symptomatic anemia
White Blood Cells
  • Rarely used
  • Gram-negative sepsis
  • Progressive soft tissue infection
Fresh Frozen Plasma
  • Prepared by separating plasma from the red blood cells and freezing it within 6 hours of collection
  • Hemorrhage
  • Expansion of plasma volume
  • Replace specific clotting factors
Factor VIII
  • Insoluble portion of plasma recovered from fresh frozen plasma
  • Von Willebrand’s disease
  • Factor VIII deficiency
  • Hemophilia A
  • Extracted from plasma
  • Contains albumin, globulin, and other proteins
  • Acute liver failure
  • Burns
  • Trauma
  • Hemolytic disease of neonates
  • Used in patients who have received multiple transfusions
  • Platelet dysfunction
  • Thrombocytopenia
  • Acute leukemia
  • Bone marrow abnormalities

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