Blood Components


                                              Blood Product Comparison

Type
Facts
Uses
 
 
Whole blood
  • Rarely used unless more than 25% of total blood volume is lost
  • Available in 500 mL bags
  • Avoid if fluid overload is a concern
  • Hemorrhage
  • Trauma
  • Major burns
 
Packed Red Blood Cells
  • Prepared by removing 90% of plasma around cells and adding anticoagulant
  • Available in 250 mL bags
  • Symptomatic anemia
Granulocytes
Or
White Blood Cells
  • Rarely used
  • Gram-negative sepsis
  • Progressive soft tissue infection
 
Fresh Frozen Plasma
  • Prepared by separating plasma from the red blood cells and freezing it within 6 hours of collection
  • Hemorrhage
  • Expansion of plasma volume
  • Replace specific clotting factors
 
Factor VIII
  • Insoluble portion of plasma recovered from fresh frozen plasma
  • Von Willebrand’s disease
  • Factor VIII deficiency
  • Hemophilia A
 
 
Albumin
  • Extracted from plasma
  • Contains albumin, globulin, and other proteins
  • Acute liver failure
  • Burns
  • Trauma
  • Hemolytic disease of neonates
 
 
Platelets
  • Used in patients who have received multiple transfusions
  • Platelet dysfunction
  • Thrombocytopenia
  • Acute leukemia
  • Bone marrow abnormalities