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hydroxyzine (Vistaril)

Page history last edited by PBworks 13 years, 1 month ago

Generic Name: hydroxyzine    Trade Names: Vistaril, Atarax

 

Classifications: antianxiety agent and sedative

 

Mechanism of Action: Due to the drugs antihitamine properties, hydroxyzine has been shown to exert a calming effect durring acute psychotic states. It is an effective antiemetic and muscle relaxant. When administered concurrently with many analgesics, it tends to potentiate their effects.

 

Pharmacokinetics:

               Onset: 15-30 min

                      Peak Effects: 1-2 hours

                      Duration: 4-6 hours

                      Half Life: 20 hours

 

Indications: nausea and vomitting, anxiety reactions, and to potentiate the effects of narcotics and synthetic narcotics

 

Contraindications: should not be administered to a patient with a hypersensitivity to the drug

 

Precautions: Hydroxyzine is given IM only. Keep the potentiating effects in mind when administering with analgesics.

 

Side Effects: sedation, dizziness, headache, dry mouth, and seizures

 

Interactions: The sedative effects of hydroxyzine can be potentiated by CNS depressants such as narcotics, sedatives, hypnotics, and alcohol.

 

Dosage: When used in the management of an acute anxiety reation use 50mg-100mg IM. The standard antiemetic dose is 25mg-50mg.

 

Considerations: It is important to investigate the cause of bizarre behavoir to determine if it is of phychiatric orgin and not diabetes, head injury, or alcohol intoxication.

 

 

 

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